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superpathway of hyoscyamine and scopolamine biosynthesis
| State Icon | Reaction | EC-Number | Confidence maximal confidence score from EnzymeDetector | |
|---|---|---|---|---|
| Tropine + (R)-phenyllactyl-CoA <=> Littorine + CoA |
2.3.1
2.3.1.185 tropine acyltransferase |
–
– |
||
| L-hyoscyamine + 2-oxoglutarate + O2 <=> 6beta-hydroxyhyoscyamine + succinate + CO2 |
1.14.11.11
hyoscyamine (6S)-dioxygenase
|
–
|
||
| 1-Methylpyrrolinium + CO2 <=> Hygrine |
not assigned |
–
|
||
| unknown_compound <=> tropinone |
not assigned |
–
|
||
| Tropine + NADP+ <=> tropinone + NADPH + H+ |
1.1.1.206
tropinone reductase I
1.1.1.236 tropinone reductase II 1.1.1.334 methylecgonone reductase |
–
– – |
||
| Hygrine <=> unknown_compound |
not assigned |
–
|
||
| Littorine <=> L-hyoscyamine |
not assigned |
–
|
||
| 6beta-hydroxyhyoscyamine + 2-oxoglutarate + O2 <=> H+ + Scopolamine + succinate + CO2 + H2O |
1.14.11.11
hyoscyamine (6S)-dioxygenase
1.14.20.13 6beta-hydroxyhyoscyamine epoxidase |
–
– |
||